The Short-Term and Long-Term Effects of Stressors on the Acquisition of Cocaine-Induced Conditioned Place Preference
作者: Wen-Yu TzengChien-Chou SuLung Yu
刊名: 調適醫學, 2014, Vol.6 (1), pp.27-31
来源数据库: Airiti Inc.
DOI: 10.4247/AM.2014.ABD062
关键词: CocaineConditioningConsolidationLearning and memoryStressor
英文摘要: The short-term and long-term modulating effects of exposure to stressors on the acquisition of cocaine-induced conditioned place preference (CPP) were examined in this study. Unconditioned foot shock was used immediately before each conditioning of cocaine-induced CPP to study the short-term modulating effect of stress on the acquisition of cocaine-induced CPP. Nonetheless, a combined stress procedure was used 4 weeks prior to the cocaine-induced CPP to examine the long-term effect of stress on the acquisition of this memory. We found that foot shock stressor did not acutely affect cocaine-induced CPP as extremely low (2.5 mg/kg/conditioning) or high (10 mg/kg/conditioning) dose of cocaine was used as conditioning dosage. In contrast, foot shock stress significantly decreased cocaine (5...
原始语种摘要: The short-term and long-term modulating effects of exposure to stressors on the acquisition of cocaine-induced conditioned place preference (CPP) were examined in this study. Unconditioned foot shock was used immediately before each conditioning of cocaine-induced CPP to study the short-term modulating effect of stress on the acquisition of cocaine-induced CPP. Nonetheless, a combined stress procedure was used 4 weeks prior to the cocaine-induced CPP to examine the long-term effect of stress on the acquisition of this memory. We found that foot shock stressor did not acutely affect cocaine-induced CPP as extremely low (2.5 mg/kg/conditioning) or high (10 mg/kg/conditioning) dose of cocaine was used as conditioning dosage. In contrast, foot shock stress significantly decreased cocaine (5...
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关键词翻译
关键词翻译
  • cocaine 可卡因
  • stressor 应激子
  • CPP Card Print Processor
  • unconditioned 无条件
  • induced 感应的
  • appetitive 欲求的
  • conditioning 
  • combined 组合
  • effect 效应
  • potent 强大的