Analgesic, Anti-Inflammatory and Anti-Oxidant Activities of Clausena anisata leaf and Stem Extracts and Quantitative and Qualitative Phytochemical Analysis of their Contents
作者: Kumatia EKAyertey FAppiah AAOcloo A
刊名: DER PHARMA CHEMICA, 2019, Vol.11 (4)
来源数据库: Scholars Research Library
关键词: PainInflammationAlkaloidCoumarinTriterpene.
原始语种摘要: Clausena anisata is a medicinal plant use to treat diseases including inflammatory, pain and oxidative stress conditions. Nonetheless, these activities have not been evaluated for its stem. This study aimed to evaluate and compared analgesic, anti-inflammatory and anti-oxidant activities of ethanol extracts of leaf (CLE) and stem (CSE) of C. anisata. Anti-inflammatory and anti-oxidant activities were assessed by carrageenan induced paw edema and DPPH free radical scavenging assays respectively. Hot plate and writhing assays were used to test the analgesic activity. Total phenolics and flavonoids were quantified using UV-Vis spectrophotometry methods. CLE and CSE produced (p<0.05) dose-depended anti-inflammatory activity (76.35-85.83%) comparable to that of indomethacin (78.26%) and (p<...
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关键词翻译
关键词翻译
  • analgesic 镇痛药
  • inflammatory 激怒的
  • extracts 摘记
  • oxidant 氧化剂
  • carrageenan 卡拉胶
  • scavenging 扫气
  • flavonoids 黄酮类似物
  • radical 
  • tramadol 曲马多
  • medicinal 医学的