Proteomic Profiling of Liver from Atlantic Salmon ( Salmo salar ) Fed Genetically Modified Soy Compared to the Near-Isogenic non-GM Line
作者: Nini H. SissenerSamuel A. M. MartinPhillip CashErnst M. HevrøyMonica SandenGro-Ingunn Hemre
作者单位: 1National Institute of Seafood and Nutrition Research (NIFES)
2School of Biological Sciences, University of Aberdeen
3Division of Applied Medicine, School of Medical Sciences, University of Aberdeen
刊名: Marine Biotechnology, 2010, Vol.12 (3), pp.273-281
来源数据库: Springer Nature Journal
DOI: 10.1007/s10126-009-9214-1
关键词: Atlantic salmonBiotechnologyGenetic modificationLiverRoundup Ready® soybean
英文摘要: Abstract(#br)The aim of this study was to investigate potential differences in liver protein expression of Atlantic salmon fed genetically modified (GM) Roundup Ready® soy at a high inclusion level (25% inclusion, constituting 21% of crude protein in the diet) for 7 months or a compositionally similar non-GM diet. The liver was selected as the target organ due to its importance in the general metabolism, and 2D gel electrophoresis used as a screening tool. Samples from 12 individual fish from each diet group were evaluated. Of a total of 781 analysed protein spots, only 36 were significantly different by ANOVA ( p < 0.05) in abundance between the diet groups. All these spots had low fold differences (1.2–1.6) and high false discovery rate ( q = 0.44), indicating minor differences in liver...
全文获取路径: Springer Nature  (合作)
影响因子:2.739 (2012)

  • salar 干盐湖
  • Atlantic 在西洋的