c-Kit proto-oncogene expression in endometrial hyperplasia and endometrial cancer
作者: Ercan YilmazOnder CelikYavuz SimsekIlgin TurkcuogluEbru CelikMehmet GülSeyma HascalikEngin Aydin
作者单位: 1Department of Obstetrics and Gynecology, Inonu University School of Medicine
2Department of Histology and Embryology, Inonu University School of Medicine
3Division of Obstetrics and Gynecology, Park Hospital
4Department of Pathology, Inonu University School of Medicine
刊名: Archives of Gynecology and Obstetrics, 2012, Vol.286 (1), pp.197-200
来源数据库: Springer Journal
DOI: 10.1007/s00404-012-2276-8
关键词: Endometrial hyperplasiaEndometriumc-KitCD117Endometrial cancer
英文摘要: Abstract(#br) Purpose(#br)To evaluate the expression of c-kit (CD117) in endometrial hyperplasia and endometrial cancer.(#br) Methods(#br)Expression of c-kit in 10 normal endometrium, 18 simple endometrial hyperplasia, 16 complex endometrial hyperplasia (10 cases with atypia and 6 cases without atypia), and 6 endometrial cancer were investigated by immunohistochemistry.(#br) Results(#br)c-Kit expression decreased as the lesion progressed to endometrial cancer. Immunostaining was mostly focal and weak in the normal endometrium and was mostly diffuse and strong in the simple and complex endometrial hyperplasia.(#br) Conclusions(#br)Simple and complex hyperplastic endometrial tissues express diffuse cytoplasmic staining for c-kit and the expression decreases with the progression of the...
全文获取路径: Springer  (合作)
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影响因子:1.33 (2012)

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关键词翻译
关键词翻译
  • endometrial 子宫内膜的
  • hyperplasia 增生
  • oncogene 肿瘤基因
  • cancer 癌症
  • proto 
  • expression 表示