Effect of cardiac resynchronization therapy on cardiotrophin-1 circulating levels in patients with heart failure
作者: Giuseppe LimongelliTeo RoselliGiuseppe PacileoPaolo CalabróValeria MaddaloniDaniele MasaroneLucia RieglerRita GravinoRaffaella ScarafileGemma SalernoTiziana MieleAntonello D’AndreaLucio SantangeloMassimo RomanoGiovanni Di SalvoMaria Giovanna RussoRaffaele Calabró
作者单位: 1Department of Cardiology, Monaldi Hospital, Second University of Naples
刊名: Internal and Emergency Medicine, 2014, Vol.9 (1), pp.43-50
来源数据库: Springer Nature Journal
DOI: 10.1007/s11739-011-0740-2
关键词: Heart failureCardiac resynchronization therapyCardiotrophin 1
英文摘要: Abstract(#br) Cardiotrophin-1 (CT-1) is a member of the interleukin (IL-6) family of cytokines. Plasma CT-1 levels correlate with the left ventricle mass index in patients with dilatated cardiomyopathy and congestive heart failure (CHF). The aim of this paper was to evaluate CT-1 plasma levels, before and after cardiac resynchronization therapy CRT, and to characterizeits prognostic role in patients with CHF. Fifty-two consecutive patients (M/F = 39/13; 56 ± 11 years old) underwent clinical and echocardiographic evaluation, and blood sample collection at baseline. The same evaluation was repeated 6.4 ± 0.79 months after CRT. Patients with a decreased LV end-systolic volume by at least 15% (reverse remodeling) were considered echo responders to CRT. Twenty-nine patients (56%) were...
全文获取路径: Springer Nature  (合作)
影响因子:2.345 (2012)

  • circulating 循环
  • cardiac 贲门
  • failure 破坏
  • heart 心脏
  • therapy 治疗