Genome-wide detection of selective signatures in Simmental cattle
作者: Huizhong FanYang WuXin QiJingjing ZhangJuan LiXue GaoLupei ZhangJunya LiHuiJiang Gao
作者单位: 1Institute of Animal Science, Chinese Academy of Agricultural Science
2College of Animal Science and Technology, Agricultural University of Jilin
刊名: Journal of Applied Genetics, 2014, Vol.55 (3), pp.343-351
来源数据库: Springer Journal
DOI: 10.1007/s13353-014-0200-6
关键词: Bovine genomeEHH testGene annotationSelection signature
英文摘要: Abstract(#br)Artificial selection has greatly improved the beef production performance and changed its genetic basis. High-density SNP markers provide a way to track these changes and use selective signatures to search for the genes associated with artificial selection. In this study, we performed extended haplotype homozygosity (EHH) tests based on Illumina BovineSNP50 (54 K) Chip data from 942 Simmental cattle to identify significant core regions containing selective signatures, then verified the biological significance of these identified regions based on some commonly used bioinformatics analyses. A total of 224 regions over the whole genome in Simmental cattle showing the highest significance and containing some important functional genes, such as GHSR, TG and CANCNA2D1 were chosen....
全文获取路径: Springer  (合作)
影响因子:1.847 (2012)

  • cattle 
  • detection 探测
  • selective 选择性的