Transcriptional Analysis of the Lysine-Responsive and Riboswitch-Regulated lysC Gene of Bacillus subtilis
作者: Trang Thi Phuong PhanWolfgang Schumann
作者单位: 1Institute of Genetics, University of Bayreuth
刊名: Current Microbiology, 2009, Vol.59 (4), pp.463-468
来源数据库: Springer Journal
DOI: 10.1007/s00284-009-9461-4
英文摘要: Abstract(#br)About 2% of the Bacillus subtilis genes are subject to regulation by riboswitch-controlled mechanisms. One of them is the l -lysine-dependent lysC gene which is turned on when the l -lysine concentration within the cytoplasm is low. In the presence of a high l -lysine concentration, only a 0.27-kb transcript is synthesized representing the riboswitch due to transcription termination. When the l -lysine concentration is low, the full-length 1.6-kb transcript is produced due to transcription anti-termination. Here, we show for the first time that even under conditions of transcription anti-termination the truncated form of the RNA is still predominant. This 0.27-kb transcript is neither the result of enhanced stability nor does it result from processing of the full-length...
全文获取路径: Springer  (合作)
影响因子:1.52 (2012)

  • subtilis 微小
  • Analysis 分析