<sup>18</sup>F-FDG PET/CT in the early prediction of pathological response in aggressive subtypes of breast cancer: review of the literature and recommendations for use in clinical trials
作者: David GroheuxDavid MankoffMarc EspiéElif Hindié
作者单位: 1Saint-Louis Hospital
2INSERM/CNRS UMR944/7212
3University of Pennsylvania Perelman School of Medicine
4University of Bordeaux
刊名: European Journal of Nuclear Medicine and Molecular Imaging, 2016, Vol.43 (5), pp.983-993
来源数据库: Springer Journal
DOI: 10.1007/s00259-015-3295-z
关键词: 18F-FDG PET/CTTriple-negative breast cancerHER2-positive breast cancerNeoadjuvant treatmentTreatment response assessmentPathological complete responsePrognosis
英文摘要: Abstract(#br)Early assessment of response to neoadjuvant chemotherapy (NAC) might be helpful in avoiding the toxicity of ineffective chemotherapy and allowing refinement of treatment. We conducted a review of the literature regarding the applicability of 18F-FDG PET/CT to the prediction of an early pathological response in different subgroups of breast cancer. Clinical research in this field has intensified in the last few years. Early studies by various groups have shown the potential of 18F-FDG PET/CT in the early assessment of response to NAC. However, interim PET/CT in breast cancer has not yet gained wide acceptance compared to its use in other settings such as lymphomas. This is in part due to a lack of consensus that early evaluation of response can be used to...
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关键词翻译
关键词翻译
  • pathological 病理学的
  • breast 胸部
  • literature 文献
  • aggressive 侵蚀的
  • PET PagE frame Table
  • cancer 癌症
  • prediction 预报
  • review 复审
  • response 响应
  • early