Association of circulating omentin-1 level with arterial stiffness and carotid plaque in type 2 diabetes
作者: Hye Jin YooSoon Young HwangHo Cheol HongHae Yoon ChoiSae Jeong YangJi A SeoSin Gon KimNan Hee KimKyung Mook ChoiDong Seop ChoiSei Hyun Baik
作者单位: 1Korea University College of Medicine
刊名: Cardiovascular Diabetology, 2011, Vol.10 (1)
来源数据库: Springer Nature Journal
DOI: 10.1186/1475-2840-10-103
关键词: omentin-1pulse wave velocitycarotid intima media thicknesstype 2 diabetes
英文摘要: Abstract(#br) Background(#br)Adipokines contribute directly to the atherosclerotic process, connecting metabolic disorders such as obesity and diabetes to cardiovascular disease. Omentin-1 is a recently discovered novel adipokine, so data about the relationship of this adipokine to vascular health in type 2 diabetes is limited.(#br) Methods(#br)We enrolled 60 people with type 2 diabetes, with or without carotid plaque, and 30 participants with normal glucose tolerance. We measured serum omentin-1, high-sensitivity C-reactive protein (hsCRP) levels, and the homeostasis model assessment of insulin resistance (HOMA-IR), as well as other cardiovascular risk factors. Vascular health was assessed by brachial ankle pulse wave velocity (baPWV) and carotid intima-media thickness (IMT).(#br)...
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影响因子:4.209 (2012)

  • plaque 
  • stiffness 刚性
  • diabetes 糖尿病
  • arterial 动脉的
  • circulating 循环
  • Association 美国公共卫生协会
  • carotid 颈动脉
  • level 水准