Long-term effects of antibiotics, norfloxacin, and sulfamethoxazole, in a partial life-cycle study with zebrafish ( Danio rerio ): effects on growth, development, and reproduction
作者: Zhenhua YanGuanghua LuQiuxia YeJianchao Liu
作者单位: 1Hohai University
2Jiangsu Province Communications Planning and Design Institute Co., Ltd.
刊名: Environmental Science and Pollution Research, 2016, Vol.23 (18), pp.18222-18228
来源数据库: Springer Nature Journal
DOI: 10.1007/s11356-016-7018-1
关键词: ZebrafishNorfloxacinSulfamethoxazoleMixtureNext generationPartial life-cycle
原始语种摘要: Abstract(#br)A partial life-cycle study with zebrafish ( Danio rerio ) was conducted to evaluate the long-term effects of antibiotics, norfloxacin (NOR) and sulfamethoxazole (SMX). A series of bio-endpoints correlated to the growth, development, and reproduction was assessed. The results showed that the body weight and the condition factor were depressed by SMX at 200 μg/L during the growth period. Meanwhile, the activities of metabolic enzyme (ethoxyresorufin O-deethylase, EROD) and antioxidant enzymes (superoxide dismutase, SOD and catalase, CAT) were stimulated in all cases. The consequences of parental exposure to antibiotics for the next generation were also examined. The egg production of parents were depressed by the 200 μg/L NOR and SMX alone or in combination. Similarly,...
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影响因子:2.618 (2012)

  • norfloxacin 诺氟沙星
  • development 开发
  • antibiotics 抗生物质
  • reproduction 复制
  • partial 局部的
  • cycle 旋回
  • growth 生长
  • effects 海员自身物品
  • study 学习