Serology describes a profile of declining malaria transmission in Farafenni, The Gambia
作者: Lotus L. van den HoogenJamie T. GriffinJackie CookNuno SepúlvedaPatrick CorranDavid J. ConwayPaul MilliganMuna AffaraStephen J. AllenCarla ProiettiSerign J. CeesayGeoffrey A. TargettUmberto D’AlessandroBrian GreenwoodEleanor M. RileyChris Drakeley
作者单位: 1London School of Hygiene and Tropical Medicine
2Imperial College London
3Centre of Statistics and Applications of University of Lisbon, Faculdade de Ciências Da Universidade de Lisboa
4Disease Control and Elimination, Medical Research Council Unit
5Liverpool School of Tropical Medicine
6QIMR Berghofer Medical Research Institute
刊名: Malaria Journal, 2015, Vol.14 (1)
来源数据库: Springer Nature Journal
DOI: 10.1186/s12936-015-0939-1
关键词: Plasmodium falciparumMalariaTransmissionSerologyMSP-119
原始语种摘要: Abstract(#br) Background(#br)Malaria morbidity and mortality has declined in recent years in a number of settings. The ability to describe changes in malaria transmission associated with these declines is important in terms of assessing the potential effects of control interventions, and for monitoring and evaluation purposes.(#br) Methods(#br)Data from five cross-sectional surveys conducted in Farafenni and surrounding villages on the north bank of River Gambia between 1988 and 2011 were compiled. Antibody responses to MSP-119 were measured in samples from all surveys, data were normalized and expressed as seroprevalence and seroconversion rates (SCR) using different mathematical models.(#br) Results(#br)Results showed declines in serological metrics with seroprevalence in...
全文获取路径: PDF下载  Springer Nature  (合作)
影响因子:3.4 (2012)

  • malaria 疟疾
  • profile 纵断图
  • transmission 传送