Toxicity of citrate-capped AuNPs: an in vitro and in vivo assessment
作者: Stefania SabellaVirgilio BrunettiGiuseppe VecchioAntonio GaleoneGabriele MaioranoRoberto CingolaniPier Paolo Pompa
作者单位: 1Center for Bio-Molecular Nanotechnology@UniLe
2Central Research Laboratories
刊名: Journal of Nanoparticle Research, 2011, Vol.13 (12), pp.6821-6835
来源数据库: Springer Journal
DOI: 10.1007/s11051-011-0590-x
关键词: NanotoxicologyGold nanoparticlesIn vitroIn vivoEnvironmentalhealth and safety (EHS)
英文摘要: Abstract(#br)In this study, we show that 15 nm citrate-capped AuNPs exert a remarkable toxicity in living systems. The assessment was performed by using well-characterized AuNPs, the combination of in vitro and in vivo models (namely two different cell lines and Drosophila melanogaster ), exposure to low dosages of nanoparticles (in the sub-nanomolar concentration range), along with the application of several biological assays to monitor different aspects of the toxic effects, such as viability, genotoxicity, and molecular biomarkers.
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来源刊物:
影响因子:2.175 (2012)

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关键词翻译
关键词翻译
  • capped 去蒂
  • assessment 评价
  • citrate 柠檬酸盐
  • vitro 体外