Single and multiple high-risk and low-risk Human Papillomavirus association with cervical lesions of 11,224 women in Jakarta
作者: Lydia S. MurdiyarsoMelissa KartawinataIffat JenieGrace WidjajahakimHeriawaty HidajatRuth SembiringI. Made NasarSantoso CornainFarid SastranagaraAhmad Rusdan Handoyo Utomo
作者单位: 1Kalbe Genomics Laboratory
2Rumah Sakit Persahabatan
3Faculty of Medicine University of Indonesia
4PT Kalbe Farma
刊名: Cancer Causes & Control, 2016, Vol.27 (11), pp.1371-1379
来源数据库: Springer Nature Journal
DOI: 10.1007/s10552-016-0816-4
关键词: HPVLBCHSILLSILCervical cancerGenotypingIndonesiaHigh-risk HPVLow-risk HPVScreening
英文摘要: Abstract(#br) Purpose(#br) We sought to evaluate prevalence, age-adjusted distribution, and impact of single and multiple high- and low-risk human papillomavirus (HPV) subtypes and their associations with cervical lesions.(#br) Methods(#br)Data were extracted from 11,224 women who underwent routine screening of HPV genotyping and liquid-based cytology co-testing. Fifteen high-risk (HR) and six low-risk (LR) HPV types were genotyped.(#br) Results(#br)Overall HPV prevalence was 10.7 %, and young women (under 21 years old) harbored highest HPV infection rate (40.38 %). The rate declined in old women 9.49 % (age 30–49) and 6.89 % (age 50 and above). Normal cytology had lowest HPV (5.66 %) compared to low-grade (60.49 %), high-grade (71.96 %) squamous intraepithelial lesions (LSIL and HSIL)...
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影响因子:3.2 (2012)

  • cervical 颈的
  • women 妇女
  • association 联合
  • multiple 多次的