Erythrocyte Deformability and Oxidative Stress in Inflammatory Bowel Disease
作者: Tulay AkmanMesut AkarsuHale AkpinarHalil ResmiEbru Sezer
作者单位: 1Department of Internal Medicine, Faculty of Medicine, Dokuz Eylul University
2Division of Gastroenterology, Faculty of Medicine, Dokuz Eylul University
3Department of Biochemistry, Faculty of Medicine, Dokuz Eylul University
4Research Laboratory, Faculty of Medicine, Dokuz Eylul University
刊名: Digestive Diseases and Sciences, 2012, Vol.57 (2), pp.458-464
来源数据库: Springer Journal
DOI: 10.1007/s10620-011-1882-9
关键词: Erythrocyte deformabilityOxidative stressCrohn diseaseUlcerative colitis
英文摘要: Abstract(#br) Background(#br)Oxidative stress and reduced microvascular flow are important factors in the pathogenesis of inflammatory bowel disease (IBD). The increased oxidative stress reduces the eriytrocyte deformability. However, in IBD, there are no studies in the literature which evaluate erythrocyte deformability.(#br) Aims(#br)In our study, we investigated the effect of oxidative stress and erythrocyte deformability in IBD.(#br) Methods(#br)Forty-three patients with active IBD, 48 patients with inactive IBD and 45 healthy controls were included. The erytrocyte deformability, malonyldialdehyde levels, glutation peroxidase and sulfhydryl levels were measured in peripheral venous blood samples.(#br) Results(#br)Erytrocyte malonyldialdehyde levels in both active and inactive IBD were...
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影响因子:2.26 (2012)

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