Isocratic liquid chromatographic determination of three paraben preservatives in hygiene wipes using a reversed phase core-shell narrow-bore column
作者: Paraskevas D. TzanavarasTheano D. KarakostaPantelis G. RigasDemetrius G. ThemelisAnastasia Zotou
作者单位: 1Laboratory of Analytical Chemistry, Department of Chemistry, Aristotelian University of Thessaloniki
2Department of Fisheries and Aquaculture Technology, Alexander Technological Educational Institute of Thessaloniki
刊名: Central European Journal of Chemistry, 2012, Vol.10 (5), pp.1459-1463
来源数据库: Springer Nature Journal
DOI: 10.2478/s11532-012-0091-5
关键词: High-performance liquid chromatographyCore-shell (or fused core) columnParabensHygiene wipes
原始语种摘要: Abstract(#br)The first HPLC method for the separation of three paraben preservatives (methyl-, ethyl- and propyl parabens) using a core-shell analytical column is reported in this study. The separation was completed in less than 8 min at a low flow rate of 0.4 mL min −1 and an isocratic mobile phase containing 20% acetonitrile as organic modifier. The backpressure was < 200 bar in all cases, enabling the usage of conventional HPLC equipment. The proposed analytical procedure was validated for linearity (0.5–20 µg L −1 ), limits of detection (15–43 µg L −1 ) and quantification (50–142 µg L −1 ), selectivity, within day (1.3–1.5%) and day-to-day (3.4–4.6%) precision and accuracy. The proposed method has been applied to the determination of the selected paraben preservatives in commercially...
全文获取路径: Springer Nature  (合作)
影响因子:1.167 (2012)

  •  狭窄的
  • reversed 倒转的
  • liquid 液体
  • phase 相位
  • determination 测定
  • shell 贝壳
  • preservatives 保存剂
  • narrow 狭窄的
  • column 狭窄的
  • three 
  • core 岩心