Monochorionic dizygotic twins with discordant sex and confined blood chimerism
作者: Hye Jin LeeSung Chul YoonJung Min KoMoon Woo SeongSung Sup ParkJin Sun ChoiSun Kyung Oh
作者单位: 1Department of Pediatrics, Seoul National University Children’s Hospital, Seoul National University College of Medicine
2Department of Laboratory Medicine, Seoul National University College of Medicine
3Institute of Reproductive Medicine and Population Medical Research Center, Seoul National University College of Medicine
刊名: European Journal of Pediatrics, 2014, Vol.173 (9), pp.1249-1252
来源数据库: Springer Nature Journal
DOI: 10.1007/s00431-014-2312-8
关键词: Monochorionic dizygotic twinDiscordant sexChimerismIn vitro fertilizationAssisted reproductive technology
英文摘要: Abstract(#br)Monochorionic (MC) pregnancy in humans is usually considered to be associated only with monozygotic twinning. However, several reports have revealed that dizygotic (DZ) twins can also share a chorion during pregnancy. A chimera is defined as an organism that contains different cells derived from two or more distinct zygotes. As artificial reproductive techniques develop, it can be predicted that the occurrence of MC DZ twins will increase, and DNA-fingerprinting methods, such as short tandem repeat (STR) analysis, will be essential for their accurate diagnosis. We report the first Korean case of MC DZ twins with blood chimerism, 46,XX/46,XY, as a consequence of in vitro fertilization/embryo transfer. The clinical phenotypes of the twins’ genitalia were complete female and...
全文获取路径: Springer Nature  (合作)
影响因子:1.907 (2012)

  • discordant 不整一的
  • dizygotic 二卵的
  • chimerism 嵌合现象
  • confined 限于
  • twins 双胎
  • blood 血液