Extra-oviductal expression of oviductal glycoprotein 1 in mouse: Detection in testis, epididymis and ovary
作者: Saniya LaheriDeepak ModiPurvi Bhatt
作者单位: 1Department of Biological Sciences, Sunandan Divatia School of Science, NMIMS University
2Molecular and Cellular Biology Laboratory, National Institute for Research in Reproductive Health (ICMR)
刊名: Journal of Biosciences, 2017, Vol.42 (1), pp.69-80
来源数据库: Springer Journal
DOI: 10.1007/s12038-016-9657-2
关键词: Epididymisovaryoviductal glycoprotein 1testis
英文摘要: Abstract(#br)Oviductal glycoprotein 1 (OVGP1), also called oviductin, is an oviduct-specific protein and is suggested to play a role in fertilization. Traditionally, Ovgp1 has been shown to be exclusively expressed by the oviduct; however, recent studies have demonstrated its expression in some cancers. This observation led us to hypothesize that Ovgp1 might have some extra-oviductal expression. In the current study, we evaluated the mRNA and protein expression of Ovgp1 in normal reproductive tissues of male and female mice. For the first time, we demonstrate that beyond the oviduct, Ovgp1 mRNA is expressed in the testis, epididymis and ovary, but not in the uterus, cervix, vagina, breast, seminal vesicles and prostate gland. In the testis, Ovgp1 mRNA was localized in the cells at the...
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影响因子:1.759 (2012)

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关键词翻译
关键词翻译
  • oviductal 输卵管的
  • glycoprotein 糖蛋白
  • epididymis 附睾
  • expression 表示
  • testis 睾丸
  • Extra 特级
  • mouse 小鼠
  • ovary 子房