Serial interferon-gamma release assays for latent tuberculosis in dialysis patients with end stage renal disease in a Korean population
作者: Seung Heon LeeHee Jin KimSeok Ju ParkTae Hee KimSo Jeong ParkSun Woo KangYeong Hoon KimDick Menzies
作者单位: 1Korea University Ansan Hospital, Korea University College of Medicine
2Korean Institute of Tuberculosis
3Inje University Busan Paik Hospital, Inje University College of Medicine
4Respiratory Epidemiology and Clinical Research Unit, Montreal Chest Institute, McGill University
刊名: BMC Infectious Diseases, 2015, Vol.15 (1)
来源数据库: Springer Nature Journal
DOI: 10.1186/s12879-015-1117-3
关键词: Interferon-gamma release assayLatent tuberculosisEnd stage renal diseaseDialysisReversion
英文摘要: Abstract(#br) Background(#br)Serial interferon-gamma-release-assay (IGRA) result can show variance due to within-subject variation and difference in host immune status, and may be affected by latent tuberculosis infection (LTBI) treatment. We aimed to know the changes in QFT-IT (QuantiFERON-TB Gold In-Tube) results measured at a 4 month interval in end stage renal disease patients and whether these changes were influenced by dialysis method or LTBI treatment.(#br) Methods(#br)We prospectively performed serial QFT-IT tests at 4 month interval in 93 end stage renal disease (ESRD) patients on HD (hemodialysis) or PD (peritoneal dialysis). LTBI treatment was given to 18 of 39 patients with initial positive QFT-IT result. Agreement between the two results was estimated for all 93 patients and...
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影响因子:3.025 (2012)

  • 释放 母体
  • dialysis 透析
  • interferon 干扰素
  • renal 肾的
  • tuberculosis 肺结核
  • gamma 伽马
  • latent 潜在的
  • population 母体
  • release 母体
  • stage 
  • Korean 朝鲜