Agreement of measured and calculated serum osmolality during the infusion of mannitol or hypertonic saline in patients after craniotomy: a prospective, double-blinded, randomised controlled trial
作者: Qian LiHan ChenJing-Jing HaoNing-Ning YinMing XuJian-Xin Zhou
作者单位: 1Capital Medical University
刊名: BMC Anesthesiology, 2015, Vol.15 (1)
来源数据库: Springer Journal
DOI: 10.1186/s12871-015-0119-4
关键词: Serum osmolalityMeasurementEstimationCorrelationMannitolHypertonic salineCraniotomy
英文摘要: Abstract(#br) Background(#br)Mannitol and hypertonic saline are used to ameliorate brain edema and intracranial hypertension during and after craniotomy. We hypothesized that the agreement of measured and calculated serum osmolality during the infusion of hypertonic saline would be better than mannitol. The objective was to determine the accuracy of serum osmolality estimation by different formulas during the administration of hyperosmolar agent.(#br) Methods(#br)A prospective, randomized, double-blinded, controlled trial was conducted in a 30-bed neurosurgical intensive care unit at a university hospital. Thirty-five adult patients requiring the use of hyperosmolar agents for prevention or treatment of brain edema after elective craniotomy were enrolled, and randomly assigned 1:1 to...
全文获取路径: PDF下载  Springer  (合作)
影响因子:1.188 (2012)

  • saline 盐的
  • mannitol 甘露糖醇
  • controlled 受控
  • infusion 浸剂
  • craniotomy 颅骨切开术
  • hypertonic 过度紧张的
  • trial 试验
  • serum 血清
  • osmolality 克分子渗透压重量浓度
  • calculated 计算的