A retrospective paired study: efficacy and toxicity of nimotuzumab versus cisplatin concurrent with radiotherapy in nasopharyngeal carcinoma
作者: H. M. LiP. LiY. J. QianX. WuL. XieF. WangH. ZhangL. Liu
作者单位: 1Sichuan University
刊名: BMC Cancer, 2016, Vol.16 (1)
来源数据库: Springer Journal
DOI: 10.1186/s12885-016-2974-x
关键词: Nasopharyngeal carcinomaNimotuzumabRadiotherapyEfficacyToxicity
英文摘要: Abstract(#br) Background(#br)To compare efficacy and toxicity of nimotuzumab versus cisplatin (CDDP) concurrent with intensity modulated radiation therapy (IMRT) in patients with nasopharyngeal carcinoma (NPC).(#br) Methods(#br)We retrospectively reviewed patients with NPC from September 2008 to November 2013. The synchronous regimens included h-R3/RT (nimotuzumab and radiotherapy) one time per week for 6–8 weeks and CDDP/RT (cisplatin and radiotherapy) every three weeks for 2–3 cycles. All patients in our analysis completed the planned IMRT and received TPF (docetaxel + cisplatin + 5-fluorouracil) neoadjuvant chemotherapy for two cycles.(#br) Results(#br)Among the 302 NPC patients who were treated definitively with TPF neoadjuvant chemotherapy followed by IMRT concurrent with nimotuzumab...
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影响因子:3.333 (2012)

  • nasopharyngeal 鼻咽的
  • cisplatin 顺氯氨铂
  • radiotherapy 放射线疗法
  • carcinoma 癌症
  • concurrent 并发的
  • retrospective 追溯
  • efficacy 效验
  • toxicity 毒性
  • versus 
  • paired 配对的