Effect of ovarian stimulation with recombinant follicle-stimulating hormone, gonadotropin-releasing hormone agonist and antagonists, on follicular fluid stem cell factor and serum urocortin 1 levels on the day of oocyte retrieval
| 作者： | Onder Celik, Ebru Celik, Ercan Yilmaz, Nilüfer Celik, Ilgın Turkcuoglu, Mustafa Ulas, Banu Kumbak, Erdal Aktan, İbrahim Ozerol |
| 作者单位： |
1Department of Obstetrics and Gynecology, Inonu University, Turgut Ozal Medical Center 2Malatya State Hospital Biochemistry 3Department of Physiology, Firat University, Medical School 4Department of Obstetrics and Gynecology, Firat University, Medical School 5Private Ege IVF center 6Department of Microbiology, Inonu University, Medical Faculty |
| 刊名： | Archives of Gynecology and Obstetrics, 2013, Vol.288 (6), pp.1417-1422 |
| 来源数据库： | Springer Journal |
| DOI： | 10.1007/s00404-013-2804-1 |
| 关键词： | Assisted reproduction; Oocyte maturation; SCF; UCN1; GnRH agonist; GnRH antagonist; |
| 英文摘要： | Abstract(#br) Purpose(#br)To compare the serum and follicular fluid (FF) concentrations of stem cell factor (SCF) as well as the serum urocortin 1 (UCN1) concentration in gonadotropin-releasing hormone antagonist (GnRH-ant) and gonadotropin-releasing hormone agonist (GnRH-a) protocols for controlled ovarian hyperstimulation (COH) in IVF patients.(#br) Methods(#br)Follicular fluids and blood samples of 42 infertile women undergoing COH for IVF-embryo transfer with either GnRH agonist ( n = 22) or GnRH antagonist ( n = 20) protocols from 2010 to 2011 were collected during oocyte retrieval. SCF concentrations of serum and FF were assessed by sandwich enzyme immunoassay using ELISA Kit for SCF kid. Serum UCN1 concentration were measured using commercially available enzyme-linked immunosorbent... |
