Single center validation of routine blastocyst biopsy implementation
作者: John B. WhitneyMitchel C. SchieweRobert E. Anderson
作者单位: 1Ovation Fertility
2Southern California Center for Reproductive Medicine
刊名: Journal of Assisted Reproduction and Genetics, 2016, Vol.33 (11), pp.1507-1513
来源数据库: Springer Nature Journal
DOI: 10.1007/s10815-016-0792-3
关键词: BlastocystBiopsyPGSValidationTrophectoderm
英文摘要: Abstract(#br) Purpose(#br)The study aims to contrast the efficacy of trophectoderm biopsy preimplantation genetic screening (PGS)/vitrification (VTF)-all cycles to past treatment protocols. Specifically, do these applied technologies increase live birth rates on a per cycle/first transfer basis?(#br) Materials and methods(#br)An observational, retrospective cohort study of first transfer outcomes was performed in two groups. Group 1 (PGS) included PGS/VTF-all cycles, and group 2 (no PGS) included the first transfer from non-PGS fresh cycles or VTF-ALL cycles. In group 1, all blastocysts were biopsied on days 5/6, vitrified and array CGH performed. Group 2 patients had embryo transfers on day 3 or day 5. All blastocysts were vitrified and warmed according to μS-VTF protocols. Clinical...
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影响因子:1.823 (2012)

  • blastocyst 胚胞
  • routine 程序
  • validation 证实
  • implementation 执行
  • biopsy 活体检视
  • center 中心