Association between omentin-1 expression in human epicardial adipose tissue and coronary atherosclerosis
作者: Yu DuQingwei JiLun CaiFangjiong HuangYongqiang LaiYue LiuJianbo YuBo HanEnjun ZhuJinwei ZhangYujie ZhouZhijian WangYingxin Zhao
作者单位: 1Beijing Institute of Heart Lung and Blood Vessel Diseases
2Capital Medical University
刊名: Cardiovascular Diabetology, 2016, Vol.15 (1)
来源数据库: Springer Journal
DOI: 10.1186/s12933-016-0406-5
关键词: Epicardial adipose tissueOmentin-1AtherosclerosisCoronary artery disease
英文摘要: Abstract(#br) Background(#br)Omentin-1, a novel adipocytokine mainly expressed in visceral adipose tissue, has been found to inhibit the inflammatory response and improve insulin resistance as well as other obesity-related disorders. This study investigated the association between omentin-1 expression in human epicardial adipose tissue (EAT) and coronary atherosclerosis.(#br) Methods(#br)Serum samples, and paired biopsies from EAT and subcutaneous adipose tissue (SAT), were obtained from patients with and without coronary artery disease (CAD, n = 28 and NCAD, n = 12, respectively) during elective cardiac surgery. Coronary angiography was performed to identify CAD presence. Serum omentin-1 and adiponectin levels were measured by ELISA. mRNA expression of omentin-1 and adiponectin was...
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影响因子:4.209 (2012)

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关键词翻译
关键词翻译
  • adipose 脂肪的
  • Association 美国公共卫生协会
  • coronary 冠状的
  • expression 表示
  • epicardial 心外膜的
  • human 人的
  • tissue 组织
  • between 在中间