Novel equine tissue miRNAs and breed-related miRNA expressed in serum
作者: Alicja PacholewskaNúria MachXavier MataAnne VaimanLaurent SchiblerEric BarreyVincent Gerber
作者单位: 1Swiss Institute of Equine Medicine, Vetsuisse Faculty, University of Bern, and Agroscope
2Institute of Genetics, Vetsuisse Faculty, University of Bern
3Animal Genetics and Integrative Biology unit (GABI), INRA, AgroParis Tech, University of Paris-Saclay
刊名: BMC Genomics, 2016, Vol.17 (1)
来源数据库: Springer Journal
DOI: 10.1186/s12864-016-3168-2
关键词: HorsemiRNAmicroRNAmiRNomeSerumsRNA-seq
英文摘要: Abstract(#br) Background(#br)MiRNAs regulate multiple genes at the post-transcriptional level and therefore play an important role in many biological processes. It has been suggested that miRNA exported outside the cells contribute to inter-cellular communication. Consequently, circulating miRNAs are of particular interest and are promising biomarkers for many diseases. The number of miRNAs annotated in the horse genome is much lower compared to model organisms like human and mouse. We therefore aimed to identify novel equine miRNAs for tissue types and breed in serum.(#br) Results(#br)We analysed 71 small RNA-seq libraries derived from nine tissues ( gluteus medius , platysma , masseter muscle, heart, liver, cartilage, bone, total blood and serum) using miRDeep2 and miRdentify tools....
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影响因子:4.397 (2012)

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关键词翻译
关键词翻译
  • equine 马的
  • breed 饲养
  • expressed 榨出的
  • related 有关的
  • serum 血清
  • tissue 组织