Surface antigen expression on peripheral blood monocytes in women with gynecologic malignancies
作者: Maciej JóźwikOsazee E OkungbowaAlina LipskaMarcin JóźwikMarzena SmoktunowiczAndrzej SemczukMichał JóźwikPiotr Radziwon
作者单位: 1Medical University of Białystok
2Regional Center for Transfusion Medicine
3University of Warmia and Mazury
4Lublin Medical University
5National Research Institute of Mother and Child
6Medical Institute, State Higher School of Computer Science and Business Administration
刊名: BMC Cancer, 2015, Vol.15 (1)
来源数据库: Springer Journal
DOI: 10.1186/s12885-015-1136-x
关键词: Cervical cancerEndometrial cancerMonocytesOvarian cancerSurface antigens
英文摘要: Abstract(#br) Background(#br)Of many specialized blood cells, monocytes are gaining increasing attention for their role in neoplastic disorders. The purpose of the present investigation was to determine the expression of selected peripheral blood monocyte surface antigens in cases of cervical, endometrial, and ovarian cancers. In addition, our aim was to validate the diagnostic value of two artificial coefficients recently proposed for the diagnosis of gynecologic malignancies: Neutrophil to Lymphocyte Ratio (NLR), and Multiplication of Neutrophil and Monocyte Counts (MNM).(#br) Methods(#br)We studied 69 white Caucasian women with histopathologic confirmation of endometrial (N = 42), cervical (N = 13), and ovarian (N = 14) cancers. Reference Group I were women suspected of cancer but...
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影响因子:3.333 (2012)

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关键词翻译
关键词翻译
  • gynecologic 妇科学的
  • peripheral 周边的
  • expression 表示
  • monocytes 单核细胞
  • women 妇女
  • antigen 抗原
  • blood 血液