Modular Tissue Assembly Strategies for Biofabrication of Engineered Cartilage
作者: B. S. SchonG. J. HooperT. B. F. Woodfield
作者单位: 1Christchurch Regenerative Medicine and Tissue Engineering (CReaTE) Group, Department of Orthopedic Surgery and Centre for Bioengineering & Nanomedicine, University of Otago
刊名: Annals of Biomedical Engineering, 2017, Vol.45 (1), pp.100-114
来源数据库: Springer Nature Journal
DOI: 10.1007/s10439-016-1609-3
关键词: Biofabrication3D bioprintingTissue assemblyCartilage tissue engineeringCell aggregateMicrotissueHydrogelMicrofabricationScaffold design
英文摘要: Abstract(#br)This review describes the prospects of applying modular assembly techniques and strategies for fabrication of advanced tissue engineered cartilage constructs. Articular cartilage is a tissue that has important functions in preserving and enabling locomotion. However, its limited intrinsic repair capacity and lack of current long-term clinical solutions makes it a candidate for repair or regeneration via tissue engineering strategies. Key advances in biofabrication and 3D bioprinting techniques allowing the specific placement of cells and tissues enable novel strategies to be adopted with increased chances of success. In particular, modular assembly, where separate biological components such as microtissue units, cellular building blocks or spheroids are combined with...
全文获取路径: Springer Nature  (合作)
影响因子:2.575 (2012)