Isolation of methyl gamma linolenate from spirulina platensis using flash chromatography and its apoptosis inducing effect
作者: Jubie S.Dhanabal S. P.Chaitanya M. V. N. L.
作者单位: 1JSS College of Pharmacy, JSS University
2J. S. S. College of Pharmacy
3JSS College of Pharmacy, Ooty-643001 JSS University
刊名: BMC Complementary and Alternative Medicine, 2015, Vol.15 (1)
来源数据库: Springer Journal
DOI: 10.1186/s12906-015-0771-8
关键词: Spirulina platensisLung cancerGamma linolenic acid (GLA)CytotoxicityFlash chromatography
英文摘要: Abstract(#br) Background(#br)Isolation of methyl gamma linolenate from Spirulina platensis using flash chromatography and its apoptosis inducing effect against human lung carcinoma A- 549 cell lines.(#br) Methods(#br)Gamma linolenic acid is an important omega-6 polyunsaturated fatty acid (PUFA) of medicinal interest was isolated from microalgae Spirulina platensis using flash chromatography system (Isolera system) as its methyl ester. The isolated methyl gamma linolenate was characterized by IR, 1H NMR, 13C NMR and mass spectral analysis and the data were consistent with the structure.(#br) Results(#br)The percentage yield of isolated methyl gamma linolenate is found to be 71 % w/w, which is a very good yield in comparison to other conventional methods. It was...
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影响因子:2.082 (2012)

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关键词翻译
关键词翻译
  • linolenate 亚麻酸盐
  • spirulina 螺旋藻属
  • effect 效应
  • gamma 伽马
  • inducing 施感的
  • methyl 甲基
  • apoptosis 细胞死
  • chromatography 色层分离法
  • flash 闪光