The association of lung function and St. George's respiratory questionnaire with exacerbations in COPD: a systematic literature review and regression analysis
作者: Amber L. MartinJessica MarvelKyle FahrbachSarah M. CadaretteTeresa K. WilcoxJames F. Donohue
作者单位: 1Evidera
2Novartis Pharmaceuticals Corporation
3University of North Carolina School of Medicine
刊名: Respiratory Research, 2016, Vol.17 (1)
来源数据库: Springer Journal
DOI: 10.1186/s12931-016-0356-1
关键词: COPDExacerbationsFEV1SGRQHealth resource utilizationRegression analysis
英文摘要: Abstract(#br) Background(#br)This study investigated the relationship between changes in lung function (as measured by forced expiratory volume in one second [FEV1]) and the St. George’s Respiratory Questionnaire (SGRQ) and economically significant outcomes of exacerbations and health resource utilization, with an aim to provide insight into whether the effects of COPD treatment on lung function and health status relate to a reduced risk for exacerbations.(#br) Methods(#br)A systematic literature review was conducted in MEDLINE, Embase, and the Cochrane Central Register of Controlled Trials to identify randomized controlled trials of adult COPD patients published in English since 2002 in order to relate mean change in FEV1 and SGRQ total score to exacerbations and...
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来源刊物:
影响因子:3.642 (2012)

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关键词翻译
关键词翻译
  • systematic 有系统的
  • questionnaire 甸表
  • literature 文献
  • analysis 分析
  • association 联合
  • respiratory 呼吸过程
  • review 复审
  • regression 海退
  • function 函数