Clinicopathological significance of orphan nuclear receptor Nurr1 expression in gastric cancer
作者: J. GuoG. ZuT. ZhouJ. XingZ. Wang
作者单位: 1Dalian Medical University
2The Second Affiliated Hospital of Dalian Medical University
3The First Affiliated Hospital of Dalian Medical University
4The Maternity and Child Care Institute of Dalian Xigang District
刊名: Clinical and Translational Oncology, 2015, Vol.17 (10), pp.788-794
来源数据库: Springer Nature Journal
DOI: 10.1007/s12094-015-1305-z
关键词: Gastric cancerImmunohistochemistryPrognosisMetastasisNurr1
英文摘要: Abstract(#br) Background(#br)Gastric cancer is the fourth most common cancer and the second leading cause of cancer-related deaths worldwide. Gastric cancer is characterized by high levels of invasion and metastasis.Increasing attention is being focused on discovering molecular markers for the diagnosis of gastric cancer and for predicting its prognosis. The objective of the present study was to evaluate Nurr1 expression in gastric cancer and to assess its correlation with clinicopathological parameters and prognosis in gastric cancer patients.(#br) Methods(#br)Tissue samples were obtained from 120 gastric cancer patients. We investigated Nurr1 expression in human normal and gastric cancer tissues using real-time reverse transcription polymerase chain reaction (qRT-PCR), western blotting,...
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影响因子:1.276 (2012)

  • orphan 孤行
  • expression 表示
  • nuclear 原子核的
  • gastric 胃的
  • receptor 接受体
  • significance 显著性
  • cancer 癌症