Inhibitory effect of purple rice husk extract on AFB 1 -induced micronucleus formation in rat liver through modulation of xenobiotic metabolizing enzymes
作者: Arpamas ChariyakornkulCharatda PunvittayagulSirinya TayaRawiwan Wongpoomchai
刊名: BMC Complementary and Alternative Medicine, 2019, Vol.19 (1), pp.1
来源数据库: Springer Nature Journal
DOI: 10.1186/s12906-019-2647-9
原始语种摘要: Rice husk, a waste material produced during milling, contains numerous phytochemicals that may be sources of cancer chemopreventive agents. Various biological activities of white and colored rice husk have been reported. However, there are few comparative studies of the cancer chemopreventive effects of white and colored rice husk. This study investigated the cancer chemopreventive activities of two different colors of rice husk using in vitro and in vivo models. A bacterial mutation assay using Salmonella typhimurium strains TA98 and TA100 was performed; enzyme induction activity in murine hepatoma cells was measured, and a liver micronucleus test was performed in male Wistar rats. The white rice husk (WRHE) and purple rice husk (PRHE) extracts were not mutagenic in Salmonella...
全文获取路径: Springer Nature  (合作)
影响因子:2.082 (2012)

  • micronucleus 小核
  • xenobiotic 生物体内异物
  • liver 
  • enzymes 酶类
  • induced 感应的
  • extracts 摘记
  • purple 紫色的
  • mutagenic 诱变的
  • Salmonella 沙门氏菌属
  • hepatoma 肝癌