Neutrophil activation and neutrophil derived neutrophil extracellular trap formation in patients with coronary artery ectasia
冠状动脉扩张症患者中性粒细胞活化与中性粒细胞源性中性粒细胞外陷阱形成
作者: Yuchao GuoRuifeng LiuLianfeng ChenWei WuShuyang Zhang
作者单位: 1Department of Cardiology, Peking Union Medical College & Chinese Academy of Medical Science, Peking Union Medical College Hospital, No. 1 Shuai Fu Yuan, 100730, Beijing, China
2Department of Cardiology, Beijing Friendship Hospital, Capital Medical University, No. 95 Yong An Road, 100050, Beijing, China
刊名: BMC Cardiovascular Disorders, 2020, Vol.20 (2), pp.420-428
来源数据库: Springer Nature Journal
DOI: 10.1186/s12872-020-01398-0
关键词: NeutrophilNeutrophil extracellular trapsCoronary artery ectasia
英文摘要: Abstract(#br)Background(#br)This study investigated neutrophil activation and neutrophil-derived extracellular traps formation in coronary artery ectasia. Methods(#br)We enrolled 90 patients who underwent coronary angiography, and included 30 patients with coronary artery ectasia (CAE), 30 patients with obstructive coronary artery disease (CAD) and 30 patients with normal coronary arteries (CON). Intra-neutrophil mean myeloperoxidase index (MPXI) was determined using an automated blood cell counter (ADVIA2120 Hematology System). Serum concentrations of plasma adhesion molecules, cytokines, and neutrophil-derived extracellular traps were quantified. Results(#br)The intra-neutrophil mean myeloperoxidase index was reduced in CAE patients compared to CAD and CON patients (1.02 ± 3.01, 3.22 ±...
全文获取路径: Springer Nature  (合作)
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影响因子:1.457 (2012)

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