GsmPlot: a web server to visualize epigenome data in NCBI
作者: Jia LiYue YinMutian ZhangJie CuiZhenhai ZhangZhiyong ZhangDeqiang Sun
作者单位: 1Center for Epigenetics & Disease Prevention, Institute of Biosciences and Technology, Texas A&M University College of Medicine, 77030, Houston, TX, USA
2Key Laboratory of Special Pathogens and Biosafety, Wuhan Institute of Virology, Chinese Academy of Sciences, 430071, Wuhan, China
3Center for Bioinformatics, School of Basic Medical Sciences, Southern Medical University, Guangzhou, China
4The Third Affiliated Hospital of Guangzhou Medical University, Guangzhou, China
刊名: BMC Bioinformatics, 2020, Vol.21 (W1), pp.487-500
来源数据库: Springer Nature Journal
DOI: 10.1186/s12859-020-3386-0
关键词: GsmPlotEpigeneticsWebserverNCBIVisualization
原始语种摘要: Abstract(#br)Background(#br)Epigenetic regulation is essential in regulating gene expression across a variety of biological processes. Many high-throughput sequencing technologies have been widely used to generate epigenetic data, such as histone modification, transcription factor binding sites, DNA modifications, chromatin accessibility, and etc. A large scale of epigenetic data is stored in NCBI Gene Expression Omnibus (GEO). However, it is a great challenge to reanalyze these large scale and complex data, especially for researchers who do not specialize in bioinformatics skills or do not have access to expensive computational infrastructure. Results(#br)GsmPlot can simply accept GSM IDs to automatically download NCBI data or can accept user’s private bigwig files as input to plot the...
全文获取路径: Springer Nature  (合作)
影响因子:3.024 (2012)