Full genomic characterization of a porcine rotavirus strain detected in an asymptomatic piglet in Accra, Ghana
作者: Samuel C. B. StubbsOsbourne QuayeMaame Ekua AcquahSamuel Mawuli AdadeyIain R. L. KeanSrishti GuptaBarbara A. Blacklaws
作者单位: 1Department of Veterinary Medicine, University of Cambridge, Cambridge, UK
2West African Centre for Cell Biology of Infectious Pathogens (WACCBIP), Department of Biochemistry, Cell and Molecular Biology, University of Ghana, P. O. Box LG 54, Volta Road, Legon, Accra, Ghana
刊名: BMC Veterinary Research, 2020, Vol.16 (1), pp.f7204-287
来源数据库: Springer Nature Journal
DOI: 10.1186/s12917-019-2226-9
关键词: Rotavirus AFull genome sequence constellationPigPorcineGhana
原始语种摘要: Abstract(#br)Background(#br)The introduction of rotavirus A vaccination across the developing world has not proved to be as efficacious as first hoped. One cause of vaccine failure may be infection by zoonotic rotaviruses that are very variable antigenically from the vaccine strain. However, there is a lack of genomic information about the circulating rotavirus A strains in farm animals in the developing world that may be a source of infection for humans. We therefore screened farms close to Accra, Ghana for animals sub-clinically infected with rotavirus A and then sequenced the virus found in one of these samples. Results(#br)6.1% of clinically normal cows and pigs tested were found to be Rotavirus A virus antigen positive in the faeces. A subset of these (33.3%) were also positive for...
全文获取路径: Springer Nature  (合作)
影响因子:1.861 (2012)