Thymus vulgaris L. and thymol assist murine macrophages (RAW 264.7) in the control of in vitro infections by Staphylococcus aureus , Pseudomonas aeruginosa , and Candida albicans
作者: Jonatas Rafael de OliveiraLeandro Wagner FigueiraFábia Lugli SperVanessa Marques MeccattiSamira Esteves Afonso CamargoLuciane Dias de Oliveira
作者单位: 1São Paulo State University (UNESP)—Institute of Science and Technology
2Universidade Estadual Paulista/UNESP—Instituto de Ciência e Tecnologia
刊名: Immunologic Research, 2017, Vol.65 (4), pp.932-943
来源数据库: Springer Nature Journal
DOI: 10.1007/s12026-017-8933-z
关键词: Thymus vulgarisThymolIn vitro infectionStaphylococcus aureusPseudomonas aeruginosaCandida albicans
英文摘要: Microorganisms are capable to combat defense cells by means of strategies that contribute to their stabilization and proliferation in invaded tissues. Frequently antimicrobial-resistant strains appear; therefore, alternative methods to control them must be investigated, for example, the use of plant products. The capacity of the thyme extract ( Thymus vulgaris L.) and phytocompound thymol in the control of in vitro infections by Staphylococcus aureus , Pseudomonas aeruginosa , and Candida albicans in murine macrophages (RAW 264.7) was evaluated. Minimal inhibitory concentrations (MIC) of the plant products were used. The effect of these MIC were analyzed in the assays of phagocytosis and immunoregulation by analysis of the production of cytokines (IL-1β, TNF-α, and IL-10) and nitric oxide...
原始语种摘要: Microorganisms are capable to combat defense cells by means of strategies that contribute to their stabilization and proliferation in invaded tissues. Frequently antimicrobial-resistant strains appear; therefore, alternative methods to control them must be investigated, for example, the use of plant products. The capacity of the thyme extract ( Thymus vulgaris L.) and phytocompound thymol in the control of in vitro infections by Staphylococcus aureus , Pseudomonas aeruginosa , and Candida albicans in murine macrophages (RAW 264.7) was evaluated. Minimal inhibitory concentrations (MIC) of the plant products were used. The effect of these MIC were analyzed in the assays of phagocytosis and immunoregulation by analysis of the production of cytokines (IL-1β, TNF-α, and IL-10) and nitric oxide...
全文获取路径: Springer Nature  (合作)
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影响因子:2.963 (2012)

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关键词翻译
关键词翻译
  • albicans 白的
  • murine 鼠灰色
  • thymol 百里酚
  • macrophages 巨噬细胞
  • phagocytosis 噬菌
  • effectively 有效地
  • Candida 坎迪德
  • vulgaris 寻常的
  • control 控制
  • cytokines 细胞浆移动