Do Eicosapentaenoic Acid Supplements Attenuate Age-Related Increases in Arterial Stiffness in Patients with Dyslipidemia?: A Preliminary Study
二十碳五烯酸( Eicosapentaenoic acid )补充是否减弱了血脂异常患者与年龄有关的动脉僵硬度增加?:一项初步研究
作者: Hirofumi TomiyamaKenji TakazawaShin-ichi OsaKen-ichi HiroseAkio HiraiToshiro IketaniMasami MondenKyo SanoyamaAkira Yamashina
作者单位: 1grid.410793.8, 0000 0001 0663 3325, Second Department of Internal Medicine, Tokyo Medical University, Tokyo, Japan
2grid.413369.a, Tokyo Medical University Kasumigaura Hospital, Ibaraki, Japan
3Kosei-cho Hospital, Tokyo, Japan
4Iketani Clinic, Tokyo, Japan
5grid.430395.8, St. Luke's International Hospital Tokyo, Tokyo, Japan
6Sanoyama Clinic, Tokyo, Japan
刊名: Hypertension Research, 2005, Vol.28 (8), pp.651-655
来源数据库: Springer Nature Journal
DOI: 10.1291/hypres.28.651
关键词: Arterial stiffnessDyslipidemiaEicosapentaenoic acid
英文摘要: Abstract(#br)The present study was conducted to examine the effect of eicosapentaenoic acid supplements on pulse wave velocity (PWV) in patients with dyslipidemia as a prospective open-labeled study. Eicosapentaenoic acid supplements (1,800 mg/day) were prescribed to 40 patients, and diet therapy in consultation with a nutritionist was conducted in 44 patients as a control group. These interventions were continued for 12 months, and PWV and blood examinations were performed at the start and end of these interventions. PWV increased in the control group but not in the eicosapentaenoic acid group. After adjustment for age, gender, the initial PWV, and the changes in mean blood pressure during the study period, a general linear model univariate analysis post hoc comparison demonstrated that...
全文获取路径: Springer Nature  (合作)
影响因子:2.791 (2012)