ELISA is superior to bacterial culture and agglutination test in the diagnosis of brucellosis in an endemic area in China
作者: Nannan XuWei WangFengzhe ChenWen LiGang Wang
作者单位: 1Department of Infectious Disease, QiLu Hospital, Shandong University, 250012, Jinan, Shandong, China
2Department of Hematopathology, The University of Texas MD Anderson Cancer Center, 77030, Houston, TX, USA
刊名: BMC Infectious Diseases, 2020, Vol.20 (5), pp.2325-2336
来源数据库: Springer Nature Journal
DOI: 10.1186/s12879-019-4729-1
关键词: BrucellosisELISA
英文摘要: Abstract(#br)Background(#br)Brucellosis is endemic in many areas in China. The current diagnosis of Brucellosis predominantly relies on the traditional bacterial culture and serum agglutination test. In this study, we aimed to explore the value of ELISA in the diagnosis of Brucellosis in Chinese population. Methods(#br)We recruited 235 patients with a diagnosis of Brucellosis at different clinical stages: 117 in acute, 78 in subacute, and 40 in chronic. We also recruited 248 control patients who presented with similar clinical symptoms but with a different diagnosis other than Brucellosis. In addition, 90 healthy volunteers were also recruited. Bacterial culture, agglutination test and ELISA assay were performed to detect Brucella spp. Results(#br)Among 235 patients with Brucellosis, 51...
全文获取路径: Springer Nature  (合作)
影响因子:3.025 (2012)