Candida krusei and Candida glabrata reduce the filamentation of Candida albicans by downregulating expression of HWP1 gene
作者: Patrícia Pimentel de BarrosFernanda FreireRodnei Dennis RossoniJuliana Campos JunqueiraAntonio Olavo Cardoso Jorge
作者单位: 1Institute of Science and Technology, Univ Estadual Paulista – UNESP
刊名: Folia Microbiologica, 2017, Vol.62 (4), pp.317-323
来源数据库: Springer Nature Journal
DOI: 10.1007/s12223-017-0500-4
关键词: CandidiasisCandida SpeciesQuorum SenseClinical StrainFarnesol
英文摘要: Pathogenicity of Candida albicans is associated with its capacity switch from yeast-like to hyphal growth. The hyphal form is capable to penetrate the epithelial surfaces and to damage the host tissues. Therefore, many investigations have focused on mechanisms that control the morphological transitions of C. albicans . Recently, certain studies have showed that non- albicans Candida species can reduce the capacity of C. albicans to form biofilms and to develop candidiasis in animal models. Then, the objective of this study was to evaluate the effects of Candida krusei and Candida glabrata on the morphogenesis of C. albicans . Firstly, the capacity of reference and clinical strains of C. albicans in forming hyphae was tested in vitro. After that, the expression of HWP1 (hyphal wall protein...
原始语种摘要: Pathogenicity of Candida albicans is associated with its capacity switch from yeast-like to hyphal growth. The hyphal form is capable to penetrate the epithelial surfaces and to damage the host tissues. Therefore, many investigations have focused on mechanisms that control the morphological transitions of C. albicans . Recently, certain studies have showed that non- albicans Candida species can reduce the capacity of C. albicans to form biofilms and to develop candidiasis in animal models. Then, the objective of this study was to evaluate the effects of Candida krusei and Candida glabrata on the morphogenesis of C. albicans . Firstly, the capacity of reference and clinical strains of C. albicans in forming hyphae was tested in vitro. After that, the expression of HWP1 (hyphal wall protein...
全文获取路径: Springer Nature  (合作)
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影响因子:0.791 (2012)

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关键词翻译
关键词翻译
  • albicans 白的
  • Candida 坎迪德
  • expression 表示
  • filamentation 成丝作用
  • reduce 减少
  • hyphal 菌丝的
  • hyphae 菌丝
  • candidiasis 念珠菌病
  • capacity 电容量
  • reference 基准电压源