Relationship between salivary/pancreatic amylase and body mass index: a systems biology approach
作者: Amélie BonnefondLoïc YengoAurélie DechaumeMickaël CanouilMaxime CastelainEstelle RogerFrédéric AllegaertRobert CaiazzoVioleta RaverdyMarie PigeyreAbdelilah ArredouaniJean-Michel BorysClaire Lévy-MarchalJacques WeillRonan RousselBeverley BalkauMichel MarreFrançois PattouThierry BrousseauPhilippe Froguel
作者单位: 1University of Lille, CNRS, Institut Pasteur de Lille, UMR 8199 – EGID
2Institute for Molecular Bioscience, The University of Queensland
3University of Lille, Inserm, U1190 – EGID
4CHU of Lille
5Qatar Biomedical Research Institute, Qatar Foundation
6Fleurbaix-Laventie Association
7Robert Debré Hospital
8Inserm, U1138, Centre de Recherche des Cordeliers
9Paris-Diderot University
10DHU-FIRE, Bichat Hospital, Assistance Publique-Hôpitaux de Paris
11Inserm, U1018, CESP, Te
刊名: BMC Medicine, 2017, Vol.15 (1)
来源数据库: Springer Nature Journal
DOI: 10.1186/s12916-017-0784-x
关键词: AMY1A/AMY2ABody mass indexCopy number variantMendelian randomizationMetabonomicsObesitySalivary/Pancreatic amylaseStarch
英文摘要: Salivary (AMY1) and pancreatic (AMY2) amylases hydrolyze starch. Copy number of AMY1A (encoding AMY1) was reported to be higher in populations with a high-starch diet and reduced in obese people. These results based on quantitative PCR have been challenged recently. We aimed to re-assess the relationship between amylase and adiposity using a systems biology approach.
原始语种摘要: Salivary (AMY1) and pancreatic (AMY2) amylases hydrolyze starch. Copy number of AMY1A (encoding AMY1) was reported to be higher in populations with a high-starch diet and reduced in obese people. These results based on quantitative PCR have been challenged recently. We aimed to re-assess the relationship between amylase and adiposity using a systems biology approach.
全文获取路径: Springer Nature  (合作)
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来源刊物:
影响因子:6.679 (2012)

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关键词翻译
关键词翻译
  • amylase 淀粉酶
  • biology 生物学
  • starch 淀粉
  • Starch 淀粉
  • pancreatic 胰的
  • hydrolyze 水解
  • approach 
  • quantitative 量的
  • salivary 唾液的
  • between 在中间