Methyl-CpG binding domain protein acts to regulate the repair of cyclobutane pyrimidine dimers on rice DNA
甲基化- CpG结合域蛋白作用于调控水稻DNA上环丁烷嘧啶二聚体的修复
作者: Changxun FangWeisi ChenChengxun LiXin JianYingzhe LiHongmei LinWenxiong Lin
作者单位: 1Fujian Provincial Key Laboratory of Agroecological Processing and Safety Monitoring, College of Life Sciences, Fujian Agriculture and Forestry University, 35002, Fuzhou, P. R. China
2Key Laboratory of Ministry of Education for Genetics, Breeding and Multiple Utilization of Crops, Fujian Agriculture and Forestry University, 350002, Fuzhou, FujianP. R. China
3Key Laboratory of Crop Ecology and Molecular Physiology of Fujian Universities, Fujian Agriculture and Forestry University, 35002, Fuzhou, P. R. China
刊名: Scientific Reports, 2016, Vol.6 (1), pp.1608-1628
来源数据库: Springer Nature Journal
DOI: 10.1038/srep34569
英文摘要: Abstract(#br)UVB radiation causes cyclobutane pyrimidine dimers (CPDs) to form on the DNA of living organisms. This study found that overexpression of the silicon absorbance gene Lsi1 reduced the accumulation of CPDs in rice, which profited from the reactivation by photolyase. The transcript abundance of deoxyribodipyrimidine photolyase (Os10g0167600 ) was generally correlated with the silicon content of the rice, and the up-regulation of Os10g0167600 was found to be highest in the UVB-treated Lsi1 -overexpressed ( Lsi1 -OX) rice. A trans-acting factor, methyl-CpG binding domain protein ( Os MeCP), was found to interact with the cis-element of Os10g0167600 . The nucleic location of Os MeCP effectively enabled the transcriptional regulation. Compared with the WT, the level of Os MeCP was...
全文获取路径: Springer Nature  (合作)
影响因子:2.927 (2012)