Reorganization of a synthetic microbial consortium for one-step vitamin C fermentation
作者: En-Xu WangMing-Zhu DingQian MaXiu-Tao DongYing-Jin Yuan
作者单位: 1Tianjin University
刊名: Microbial Cell Factories, 2016, Vol.15 (1)
来源数据库: Springer Nature Journal
DOI: 10.1186/s12934-016-0418-6
关键词: Synthetic microbial consortiumReorganizationOne-step fermentationInteractionMetabolomics
英文摘要: Abstract(#br) Background(#br)In the industry, the conventional two-step fermentation method was used to produce 2-keto- l -gulonic acid (2-KGA), the precursor of vitamin C, by three strains, namely, Gluconobacter oxydans , Bacillus spp. and Ketogulonicigenium vulgare . Despite its high production efficiency, the long incubation period and an additional second sterilization process inhibit the further development. Therefore, we aimed to reorganize a synthetic consortium of G. oxydans and K. vulgare for one-step fermentation of 2-KGA and enhance the symbiotic interaction between microorganisms to perform better.(#br) Results(#br)During the fermentation, competition for sorbose of G. oxydans arose when co-cultured with K. vulgare . In this study, the competition between the two microbes was...
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影响因子:3.306 (2012)

  • vitamin 维生素
  • synthetic 合成的
  • fermentation 发酵
  • microbial 微生物的
  • consortium 同生群