Evaluation of MLVA for epidemiological typing and outbreak detection of ESBL-producing Escherichia coli in Sweden
作者: Lisa HelldalNahid KaramiChristina Welinder-OlssonEdward R. B. MooreChristina Åhren
作者单位: 1Sahlgrenska Academy and Centre for Antibiotic Resistance Research (CARe) at the University of Gothenburg
2Clinical Microbiology/Section for Bacteriology, Sahlgrenska University Hospital
3Swedish strategic programme against antibiotic resistance, Region Västra Götaland
刊名: BMC Microbiology, 2017, Vol.17 (1)
来源数据库: Springer Nature Journal
DOI: 10.1186/s12866-016-0922-1
关键词: ESBLEscherichia coliO25b-ST131H30-Rx ST131Epidemiological typingMLVA
英文摘要: To identify the spread of nosocomial infections and halt outbreak development caused by Escherichia coli that carry multiple antibiotic resistance factors, such as extended-spectrum beta-lactamases (ESBLs) and carbapenemases, is becoming demanding challenges due to the rapid global increase and constant and increasing influx of these bacteria from the community to the hospital setting. Our aim was to assess a reliable and rapid typing protocol for ESBL- E. coli , with the primary focus to screen for possible clonal relatedness between isolates. All clinical ESBL- E. coli isolates, collected from hospitals ( n = 63) and the community ( n = 41), within a single geographical region over a 6 months period, were included, as well as clinical isolates from a polyclonal outbreak (ST131, n = 9,...
原始语种摘要: To identify the spread of nosocomial infections and halt outbreak development caused by Escherichia coli that carry multiple antibiotic resistance factors, such as extended-spectrum beta-lactamases (ESBLs) and carbapenemases, is becoming demanding challenges due to the rapid global increase and constant and increasing influx of these bacteria from the community to the hospital setting. Our aim was to assess a reliable and rapid typing protocol for ESBL- E. coli , with the primary focus to screen for possible clonal relatedness between isolates. All clinical ESBL- E. coli isolates, collected from hospitals ( n = 63) and the community ( n = 41), within a single geographical region over a 6 months period, were included, as well as clinical isolates from a polyclonal outbreak (ST131, n = 9,...
全文获取路径: Springer Nature  (合作)
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影响因子:3.104 (2012)

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关键词翻译
关键词翻译
  • Escherichia 埃希氏菌属
  • outbreak 爆发
  • typing 打字
  • isolates 单离体
  • PFGE 脉冲场凝胶电泳
  • extended 扩展
  • nosocomial 医院的
  • polyclonal 多元性繁殂系的
  • community 群落
  • locus 轨迹