Current approach for detection of sub-clinical left ventricular dysfunction associated with chemotherapy
作者: Katarzyna KorzeniowskaJerzy JankowskiArtur CieślewiczAnna Jabłecka
作者单位: 1Poznan University of Medical Sciences,Poznań,Poland
刊名: Pharmacological Reports, 2015, Vol.67 (8), pp.1098-1102
来源数据库: Springer Nature Journal
DOI: 10.1016/j.pharep.2015.03.010
关键词: CardiotoxicityLeft ventricular dysfunctionEchocardiographyGlobal longitudinal strainTroponin
英文摘要: Abstract(#br)The article describes the current knowledge concerning approaches for detection of sub-clinical left ventricular dysfunction associated with chemotherapy. The authors focused on the problem of defining cardiotoxicity as well as diagnostic methods, which may be useful in predicting the occurrence of such complications. Currently, cardiac biomarkers measurement (troponin, NT-proBNP), tissue Doppler-based strain imaging and peak systolic longitudinal strain rate are most useful for detection of early myocardial changes during therapy, whereas speckle tracking echocardiography (STE) and peak systolic global longitudinal strain (GLS) appear to be the best measure. The problem of cardiotoxicity requires close cooperation between oncologists and cardiologists, particularly in light...
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影响因子:1.965 (2012)

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