Prevalence and genetic characteristics of Saffold cardiovirus in China from 2009 to 2012
作者: Xiao-Ai ZhangQing-Bin LuYing WoJin ZhaoDou-Dou HuangChen-Tao GuoHong-Mei XuEn-Mei LiuWei LiuWu-Chun Cao
作者单位: 1State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, 100071, Beijing, P.R. China
2School of Public Health, Peking University, 100191, Beijing, P.R. China
3Graduate School of Anhui Medical University, 230032, Hefei, P.R. China
4Children's Hospital of Chongqing Medical University, 400014, Chongqing, P.R. China
刊名: Scientific Reports, 2015, Vol.5 (1), pp.27-29
来源数据库: Springer Nature Journal
DOI: 10.1038/srep07704
英文摘要: Abstract(#br)The epidemiology and clinical features of the Saffold cardiovirus (SAFV) remain ambiguous. The present study was designed to systematically and intensively investigate the epidemiological features of SAFV in pediatric patients in China. Three cohorts of pediatric patients were recruited from 2009 to 2012. Cohort 1 comprised patients with acute respiratory tract infections. Cohort 2 comprised patients with diarrhea. Cohort 3 comprised hand, foot and mouth disease (HFMD) patients. A total of 115 patients (1.6%) among 6052 (17/1647, 12/2013 and 86/2392 in cohorts 1, 2 and 3, respectively) were SAFV-positive. The samples from 82 SAFV-positive patients were successfully sequenced and four genotypes were identified: 8 SAFV-1, 41 SAFV-2, 29 SAFV-3 and 4 SAFV-6. A significantly...
全文获取路径: Springer Nature  (合作)
影响因子:2.927 (2012)