Multi-institutional phase II study on the feasibility of liver resection following preoperative mFOLFOX6 therapy for resectable liver metastases from colorectal cancers
作者: Satoshi NagayamaSuguru HasegawaKoya HidaKenji KawadaEtsuro HatanoKojiro NakamuraSatoru SeoKojiro TauraKentaro YasuchikaTakashi MatsuoMasazumi ZaimaAkiyoshi KanazawaHiroaki TerajimaMasaharu TadaYukihito AdachiRyuta NishitaiDai ManakaTsunehiro YoshimuraKoji DoiTakahiro HorimatsuAkira MitsuyoshiKenichi YoshimuraMiyuki NiimiShigemi MatsumotoYoshiharu SakaiShinji Uemoto
作者单位: 1Graduate School of Medicine, Kyoto University
2Shiga Medical Center for Adults
3Osaka Red Cross Hospital
4Kitano Hospital
5Saiseikai Noe Hospital
6Kyoto Katsura Hospital
7Tenri Yorozu Hospital
8Fukui Red Cross Hospital
9Kyoto University Hospital
10Mitsubishi Kyoto Hospital
刊名: International Journal of Clinical Oncology, 2017, Vol.22 (2), pp.316-323
来源数据库: Springer Journal
DOI: 10.1007/s10147-016-1050-5
关键词: Colorectal liver metastasisPreoperative mFOLFOX6 therapyLiver resection
英文摘要: Although liver resection combined with preoperative chemotherapy is expected to improve outcomes of patients with resectable colorectal liver metastasis (CRLM), there is as yet insufficient clinical evidence supporting the efficacy of preoperative systemic chemotherapy. The aim of this phase II study was to assess the feasibility and efficacy of preoperative FOLFOX systemic chemotherapy for patients with initially resectable CRLM.
原始语种摘要: Although liver resection combined with preoperative chemotherapy is expected to improve outcomes of patients with resectable colorectal liver metastasis (CRLM), there is as yet insufficient clinical evidence supporting the efficacy of preoperative systemic chemotherapy. The aim of this phase II study was to assess the feasibility and efficacy of preoperative FOLFOX systemic chemotherapy for patients with initially resectable CRLM.
全文获取路径: Springer  (合作)
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影响因子:1.727 (2012)

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关键词翻译
关键词翻译
  • preoperative 操作前的
  • liver 
  • resectable 可切除的
  • resection 后方交会
  • chemotherapy 化学疗法
  • feasibility 可行性
  • colorectal 结肠直肠的
  • metastases 移位变化
  • metastasis 同质蜕变
  • efficacy 效验