High expression of GRP78/BiP as a novel predictor of favorable outcomes in patients with advanced thymic carcinoma
作者: Yosuke MiuraKyoichi KairaReiko SakuraiHisao ImaiYoshio TomizawaNoriaki SunagaKoichi MinatoTakeshi HisadaTetsunari OyamaMasanobu Yamada
作者单位: 1Gunma Prefectural Cancer Center
2Gunma University Graduate School of Medicine
3National Hospital Organization Shibukawa Medical Center
4Gunma University Hospital
刊名: International Journal of Clinical Oncology, 2017, Vol.22 (5), pp.872-879
来源数据库: Springer Journal
DOI: 10.1007/s10147-017-1142-x
关键词: Thymic carcinomaGlucose-regulated protein 78/immunoglobulin heavy chain binding proteinEndoplasmic reticulum stressPrognostic factorBiomarker
英文摘要: Glucose-regulated protein (GRP) 78/immunoglobulin heavy chain binding protein (BiP) is a member of the endoplasmic reticulum chaperone family, and its role in various types of human malignancies has recently been investigated. However, the clinicopathological characteristics of GRP78/BiP in advanced thymic carcinoma (ATC) remain unknown. We aimed to examine the relationship between GRP78/BiP expression and the clinical outcomes of ATC patients.
原始语种摘要: Glucose-regulated protein (GRP) 78/immunoglobulin heavy chain binding protein (BiP) is a member of the endoplasmic reticulum chaperone family, and its role in various types of human malignancies has recently been investigated. However, the clinicopathological characteristics of GRP78/BiP in advanced thymic carcinoma (ATC) remain unknown. We aimed to examine the relationship between GRP78/BiP expression and the clinical outcomes of ATC patients.
全文获取路径: Springer  (合作)
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影响因子:1.727 (2012)

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关键词翻译
关键词翻译
  • thymic 胸腺的
  • carcinoma 癌症
  • immunoglobulin 免疫球蛋白
  • predictor 预示
  • expression 表示
  • protein 蛋白质
  • favorable 好意的
  • GRP 
  • reticulum 蜂巢胃
  • regulated 规定