Substrates and oxygen dependent citric acid production by Yarrowia lipolytica : insights through transcriptome and fluxome analyses
作者: Wael SabraRajesh Reddy BommareddyGarima MaheshwariSeraphim PapanikolaouAn-Ping Zeng
作者单位: 1Hamburg University of Technology
2University of Nottingham
3Agricultural University of Athens
刊名: Microbial Cell Factories, 2017, Vol.16 (1)
来源数据库: Springer Journal
DOI: 10.1186/s12934-017-0690-0
关键词: Citric acidDual substrateOleaginous yeastPentose phosphate pathwayGlyoxylate cycle
英文摘要: Unlike the well-studied backer yeast where catabolite repression represents a burden for mixed substrate fermentation, Yarrowia lipolytica , an oleaginous yeast, is recognized for its potential to produce single cell oils and citric acid from different feedstocks. These versatilities of Y. lipolytica with regards to substrate utilization make it an attractive host for biorefinery application. However, to develop a commercial process for the production of citric acid by Y. lipolytica , it is necessary to better understand the primary metabolism and its regulation, especially for growth on mixed substrate.
原始语种摘要: Unlike the well-studied backer yeast where catabolite repression represents a burden for mixed substrate fermentation, Yarrowia lipolytica , an oleaginous yeast, is recognized for its potential to produce single cell oils and citric acid from different feedstocks. These versatilities of Y. lipolytica with regards to substrate utilization make it an attractive host for biorefinery application. However, to develop a commercial process for the production of citric acid by Y. lipolytica , it is necessary to better understand the primary metabolism and its regulation, especially for growth on mixed substrate.
全文获取路径: Springer  (合作)
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影响因子:3.306 (2012)

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关键词翻译
关键词翻译
  • production 生产
  • through 经过
  • citric 柠檬性的
  • especially 特别地
  • necessary 必要的
  • substrate 基质
  • process 过程
  • yeast 酵母
  • recognized 被公认的
  • phosphate 磷酸盐