Local anaesthetics or their combination with morphine and/or magnesium sulphate are toxic for equine chondrocytes and synoviocytes in vitro
作者: L. M. Rubio-MartínezE. RiojaM. Castro MartinsS. WipaweeP. CleggM. J. Peffers
作者单位: 1University of Liverpool, Leahurst Campus
2Rajamangala University of Technology Srivijaya (Thailand) and Institute of Aging and Chronic Disease, University of Liverpool
3University of Liverpool
刊名: BMC Veterinary Research, 2017, Vol.13 (1)
来源数据库: Springer Journal
DOI: 10.1186/s12917-017-1244-8
关键词: Local anaestheticMorphineMagnesium sulphateChondrocyteSynoviocyteEquine
英文摘要: Chondrotoxic effects of local anaesthetics are well reported in humans and some animal species but knowledge on their toxic effects on synoviocytes or equine chondrocytes or the effects on cellular production of inflammatory cytokines is limited. The purpose of this study was to evaluate the in vitro effects of local anaesthetics, morphine, magnesium sulphate (MgSO4) or their combinations on cell viability and pro-inflammatory cytokine gene expression of equine synoviocytes and chondrocytes.
原始语种摘要: Chondrotoxic effects of local anaesthetics are well reported in humans and some animal species but knowledge on their toxic effects on synoviocytes or equine chondrocytes or the effects on cellular production of inflammatory cytokines is limited. The purpose of this study was to evaluate the in vitro effects of local anaesthetics, morphine, magnesium sulphate (MgSO4) or their combinations on cell viability and pro-inflammatory cytokine gene expression of equine synoviocytes and chondrocytes.
全文获取路径: Springer  (合作)
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影响因子:1.861 (2012)

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关键词翻译
关键词翻译
  • morphine 吗啡
  • anaesthetic 麻醉剂
  • sulphate 硫酸盐
  • equine 马的
  • magnesium 
  • their 他们的
  • cytokines 细胞浆移动
  • toxic 有毒的
  • effects 海员自身物品
  • vitro 体外