Adipic acid tolerance screening for potential adipic acid production hosts
作者: Emma KarlssonValeria MapelliLisbeth Olsson
作者单位: 1Chalmers University of Technology
2Sacco S.r.l.
刊名: Microbial Cell Factories, 2017, Vol.16 (1)
来源数据库: Springer Journal
DOI: 10.1186/s12934-017-0636-6
关键词: Adipic acidToleranceScreening
英文摘要: Biobased processes for the production of adipic acid are of great interest to replace the current environmentally detrimental petrochemical production route. No efficient natural producer of adipic acid has yet been identified, but several approaches for pathway engineering have been established. Research has demonstrated that the microbial production of adipic acid is possible, but the yields and titres achieved so far are inadequate for commercialisation. A plausible explanation may be intolerance to adipic acid. Therefore, in this study, selected microorganisms, including yeasts, filamentous fungi and bacteria, typically used in microbial cell factories were considered to evaluate their tolerance to adipic acid.
原始语种摘要: Biobased processes for the production of adipic acid are of great interest to replace the current environmentally detrimental petrochemical production route. No efficient natural producer of adipic acid has yet been identified, but several approaches for pathway engineering have been established. Research has demonstrated that the microbial production of adipic acid is possible, but the yields and titres achieved so far are inadequate for commercialisation. A plausible explanation may be intolerance to adipic acid. Therefore, in this study, selected microorganisms, including yeasts, filamentous fungi and bacteria, typically used in microbial cell factories were considered to evaluate their tolerance to adipic acid.
全文获取路径: Springer  (合作)
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来源刊物:
影响因子:3.306 (2012)

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关键词翻译
关键词翻译
  • screening 筛分
  • production 生产
  • filamentous 丝状的
  • typically 典型地
  • tolerance 耐性
  • demonstrated 探明的储量
  • several 各自
  • evaluate 求...的值
  • potential 
  • detrimental 损害