Is the impact of childhood influenza vaccination less than expected: a transmission modelling study
作者: Felix WeidemannCornelius RemschmidtSilke BudaUdo BuchholzBernhard UltschOle Wichmann
作者单位: 1Robert Koch-Institute
刊名: BMC Infectious Diseases, 2017, Vol.17 (1)
来源数据库: Springer Journal
DOI: 10.1186/s12879-017-2344-6
关键词: InfluenzaChildhood vaccinationTransmission modelNNVBayesian inference
英文摘要: To reduce the burden of severe influenza, most industrialized countries target specific risk-groups with influenza vaccines, e.g. the elderly or individuals with comorbidities. Since children are the main spreaders, some countries have recently implemented childhood vaccination programs to reduce overall virus transmission and thereby influenza disease in the whole population. The introduction of childhood vaccination programs was often supported by modelling studies that predicted substantial incidence reductions. We developed a mathematical transmission model to examine the potential impact of childhood influenza vaccination in Germany, while also challenging established modelling assumptions.
原始语种摘要: To reduce the burden of severe influenza, most industrialized countries target specific risk-groups with influenza vaccines, e.g. the elderly or individuals with comorbidities. Since children are the main spreaders, some countries have recently implemented childhood vaccination programs to reduce overall virus transmission and thereby influenza disease in the whole population. The introduction of childhood vaccination programs was often supported by modelling studies that predicted substantial incidence reductions. We developed a mathematical transmission model to examine the potential impact of childhood influenza vaccination in Germany, while also challenging established modelling assumptions.
全文获取路径: Springer  (合作)
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来源刊物:
影响因子:3.025 (2012)

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关键词翻译
关键词翻译
  • vaccination 注射疫苗
  • influenza 列性感冒
  • childhood 幼年
  • modelling 模型制造
  • transmission 传送
  • vaccines 疫苗
  • impact 冲击碰撞
  • potential 
  • expected 预期
  • challenging 有希望的