Long-term microfluidic tracking of coccoid cyanobacterial cells reveals robust control of division timing
作者: Feiqiao Brian YuLisa WillisRosanna Man Wah ChauAlessandro ZambonMark HorowitzDevaki BhayaKerwyn Casey HuangStephen R. Quake
作者单位: 1Stanford University
2Cambridge University
3University of Padova
4Carnegie Institution for Science
5Stanford University School of Medicine
6Chan Zuckerberg Biohub
刊名: BMC Biology, 2017, Vol.15 (1)
来源数据库: Springer Nature Journal
DOI: 10.1186/s12915-016-0344-4
关键词: CyanobacteriaMicrofluidicsSingle-cell imagingLight-dark cyclesCell-size homeostasisCircadian clockPhotosynthesis
原始语种摘要: Cyanobacteria are important agents in global carbon and nitrogen cycling and hold great promise for biotechnological applications. Model organisms such as Synechocystis sp . and Synechococcus sp . have advanced our understanding of photosynthetic capacity and circadian behavior, mostly using population-level measurements in which the behavior of individuals cannot be monitored. Synechocystis sp . cells are small and divide slowly, requiring long-term experiments to track single cells. Thus, the cumulative effects of drift over long periods can cause difficulties in monitoring and quantifying cell growth and division dynamics.
全文获取路径: Springer Nature  (合作)
影响因子:6.531 (2012)

  • timing 计时
  • division 
  • cells 麻风细胞
  • photosynthetic 光合的
  • population 母体
  • tracking 跟踪
  • coccoid 球菌样的
  • circadian 昼夜节律
  • promise 允诺
  • understanding 理解